CLINICAL MANIFESTATION OF LATE NEONATAL SEPSIS – CONTINU-OUS DIFFERENTIAL DIAGNOSTIC DILEMMA
Matej Katavić, Andrea Dasović Buljević
Neonatal sepsis as a clinical syndrome is one of the most common challenges in neonatal medicine with a relatively high mortality rate. At the time of clinical manifestation it can be distinguished into early onset and late onset sepsis, highly depending on sources and medical experts opinions.Its multiorgan affection can be associated with major complications and high late morbidity and mortality. The period of the second week of life is the primary interest of this paper, because children who were thought to be healthy are discharged home from the maternity ward, more or less successfully adapted to extrauterine life with the possibility of developing serial noninfectious conditions and diseases that clinically impress as sepsis. Such state can make serious differental diagnostic difficulty and requires quick reaction with timely and appropriate therapy that could be crucial in the management of these patients. Definitive care should be continued in an adequate institution, depending on diagnosis. The aim of this review is pointing out the wide range of noninfectious conditions that can present as late onset neonatal sepsis.