WHAT SHOULD WE KNOW ABOUT CONTACT HYPERSENSITIVITY TO LOCAL GLUCOCORTICOIDS?
Summary. Local glucocorticoids are still the most frequently used drugs in dermatology. In recent years there have been an increasing number of reports on contact allergic reactions to glucocorticoid. Patients with contact allergy to glucocorticoid generally present with chronic dermatitis that is exacerbated by and fails to respond to glucocorticoid therapy. Most patients react in patch test to more than one glucocorticoid, but mostly to tixocortol pivalate and budesonide.In patients with pro- longed eczematous skin disease and other chronic inflammatory disease who do not improve, or who deteriorate during topi- cal glucocorticoid therapy, contact allergy should be suspected and patch test should be preformed.