EFFICACY OF UTEROBRUSH IN ENDOMETRIAL SAMPLE COLLECTION FOR THE CYTOLOGY AND DIAGNOSIS OF ENDOMETRIAL LESIONS
Ines Krivak Bolanča, Suzana Katalenić Simon, Tanja Bota, Danijela Vincetić
Objective: Endometrial carcinoma is the most common invasive neoplasm of the female genital tract, with a rising incidence over the past few decades. The aim of the study was to evaluate the efficacy of endometrial cytology using uterobrush in the collection of samples and diagnosis of endometrial lesions. Methods and examinees: During the 12-month period direct endometrial samples by uterobrush were collected from 162 perimenopausal or postmenopausal symptomatic patients at Gynaecology Department at Merkur University Hospital. Results were compared with histology of the endometrium obtained by dilatation and curettage (n= 36), or hysterectomy (n=16), or the patients follow –up mainly by ultrasonography (n=97). Inadequate samples were excluded from the study. Results: Cytological findings were confirmed by histology in 69.2% (36/52) of cases. Seven cancers, 13 hyperplasias, one polyp and 14 benign disorders were diag-nosed and confirmed by histology. After using uterobrush device, patients who were followed-up by ultrasonography showed no gynaecological symptoms. Conclusion: Endometrial cytology by using uterobrush method can provide direct, adequate and representative endometrial sample. Cytology can recognise endometrial lesions and provide data for an algorithm for further evalua-tion of symptomatic patients.