Summary. The aim of treatment for benign prostatic hyperplasia is relieving lower urinary tract symptoms, desreasing blad- der outlet obstruction, improving bladder emptying, ameliorating detrusor instability, reversing renal insufficiency, and pre- venting future episodes of gross hematuria, urinary tract infection and urinary retention. A potent role of medical therapy is to prevent the development and/or progression of benign prostatic hyperplasia. Medical therapies investigated for benign prostatic hyperplasia include plant extracts, alpha adrenergic blockers and 5-alpha-reductase inhibitors. Clinical observa- tions suggest that the efficacy of combination therapy could be superior to that of individual monotherapies.