PATHOHISTOLOGICAL DIAGNOSIS OF PROSTATIC CARCINOMA IN NEEDLE CORE BIOPSIES
Autori:
Božo Krušlin, Davor Tomas, Borislav Spajić
Sažetak
Sažetak. Karcinom prostate najčešći je visceralni zloćudni tumor muškaraca koji je i drugi uzrok smrti u muškaraca zbog zloćudnih tumora. Najčešće se pojavljuje u starijih od 50 godina, a sve se češće otkriva u asimptomatskoj fazi s pomoću jednostavnih i lako dostupnih testova određivanja PSA i posljedične biopsije iglom. Ovakav pristup omogućava pravodobno liječenje čime se značajno poboljšava prognoza odnosno postiže izlječenje bolesnika. U ovom tekstu opisujemo postupke i mogućnosti rane patohistološke dijagnostike s pomoću biopsije širokom iglom. Osim toga opisujemo najčešće histološke podtipove karcinoma prostate i različita netumorska stanja koja mogu oponašati karcinom i na koja treba misliti u diferencijalnoj dijagnostici da se ne bi postavila lažno pozitivna dijagnoza i tako izbjegle nepotrebne prostatektomije.
Summary
Summary. Prostate cancer is the most common visceral tumor in males. It is the second most common cause of death in males due to malignant tumors. It usually appears in persons older than 50 years. It can be detected in asymptomatic patients by a simple and easily accessible procedure that includes prostate specific antigen measurement and needle core biopsy. Such an approach enables adequate treatment, insures better prognosis and even cures the patients. We describe the needle core biopsy approach and its potential in the early pathohistological diagnosis of prostate cancer. We also describe the most common histological types of prostate carcinoma as well as various nontumorous mimickers which should be considered in the differential diagnosis, in order to avoid false positive diagnosis and unnecessary prostatectomies.
