Assessment of effect of peripheral laser iridotomy on biometric parameters of anterior eye segment in pigmentary glaucoma
Autori:
Dina Lešin Gaćina, Smiljka Popović-Suić, Sonja Jandroković, Tomislav Jukić, Josip Knežević, Petra Kristina Ivkić
Sažetak
Summary
Pigmentary glaucoma (PG) is a secondary open-angle glaucoma associated with pigment dispersion syndrome in which progressive optic-nerve damage occurs leading to visual field loss. The aim of the study was to investigate the effect of peripheral laser iridotomy (PLI) on the biometric parameters of anterior eye segment measured by anterior-segment optical coherence tomography (AS OCT) and difference in the value of intraocular pressure, before and six months after the application of PLI in patients with PG. Material and methods: A prospective cross-sectional study was performed on 15 subjects (total of 30 eyes) with a diagnosis of PG, at the Department of Ophthalmology, Clinical Hospital Centre Zagreb. All subjects included in the study underwent Nd:YAG PLI. Intraocular pressure values were measured by Goldmann applanation tonometry. AS OCT (Visante™ OCT, Carl Zeiss) was performed to establish anterior chamber parameters, including anterior chamber angle in temporal quadrant and anterior chamber depth, before and six months after PLI. Differences in baseline and postoperative measurements were analyzed. Results have shown that the use of PLI in pigmentary glaucoma subjects leads to reducing of anterior chamber angle and anterior chamber depth (p<0.001) and lowering intraocular
pressure (p<0.005) at the end of the six-month follow up. Conclusion: PLI has shown beneficial outcomes on biometric parameters of anterior eye segment and on intraocular pressure values. The method is safe for patients, painless and can be performed in everyday clinical practice.