THE ULTRASOUND CHARACTERISTICS OF KIDNEYS IN CHILDREN AND ADOLESCENTS WITH DIABETES MELLITUS TYPE 1
Autori:
Evlijana Hasanović, Denijal Tulumović, Goran Imamović, Senaid Trnačević
Sažetak
Sažetak. Cilj rada bio je usporediti ultrazvučni nalaz morfometrijskih mjerenja i registracije Dopplerovih signala bubrega među djecom i adolescentima s dijabetesom melitusom tipa 1 (DMT1) s mikroalbuminurijom i metaboličkom kontrolom u odnosu na trajanje bolesti. U retrospektivno-prospektivnu studiju uključeno je 80 ispitanika, oboljelih od DMT1 u dobi od 2 do 16 godina. Svi ispitanici podijeljeni su u dvije grupe: jedna grupa s trajanjem DMT1 kraćim od 10 godina i druga grupa s više od 10 godina. Ispitanici s trajanjem DMT1 dužim od 10 godina imaju učestalije mikroalbuminuriju, povećan volumen desnog bubrega, veći HbA1C i povišen indeks rezistencije u arteriji interlobaris. Pored mikroalbuminurije, praćenje dimenzija i volumena bubrega može upozoriti na postojanje ranih faza dijabetičke nefropatije.
Summary
Summary. The aim of the study was to compare ultrasound findings of morphometric measurements and registration of Doppler signs of kidneys between children and adolescents with diabetes mellitus type 1 (DMT1) with microalbuminuria, and metabolic control with duration of the disease. Retrospective-prospective study included 80 patients, who got DMT1 in the age from 2 to 16 years. In relation to the duration of the disease, all patients were divided into two groups: the first was whose illness had lasted less than 10 years, the second group was with duration of DMT1 more than 10 years. In patients with duration of DMT1 more than 10 years, the frequency of microalbuminuria, pathological findings of the volume of right kidney, and higher HbA1C were significantly greater. The significant difference was found in the frequency of pathological findings of the resistance index (RI) in the interlobar arteries in both kidneys. Alongside microalbuminuria, monitoring the dimension and volume of the kidneys may indicate the existence of the early phases of diabetic nephropathy.
