DIAGNOSTIC-THERAPEUTIC GUIDELINES FOR MEN WHOSE PARTNERS HAVE HPV GENITAL INFECTION

Autori:

Suzana Ljubojević, Jasna Lipozenčić, Mihael Skerlev, Lidija Žele-Starčević, Nikola Ljubojević, Damir Babić, Goran Grubišić, Stanko Jukić

Sažetak

Sažetak. Infekcija humanim papilomavirusom (HPV) smatra se najčešćom spolno prenosivom bolešću. Povezane su s različitim promjenama, od benignih veruka, akuminiranih kondiloma pa sve do malignih karcinoma cerviksa, vulve, vagine, penisa i anusa. Peniskopija se uz HPV-genotipizaciju dokazala specifičnom dijagnostičkom metodom u otkrivanju supkliničke HPV-genitalne infekcije u asimptomatskih muškaraca. Uzimanje uzoraka za dokaz HPV-infekcije u asimptomatskih muškaraca kohlejom kvalitetniji je način dobivanja uzorka od uzimanja obriska štapićem ili špatulom. Pravo¬vremena dijagnoza i liječenje HPV-infekcije u muškaraca od potencijalne je koristi jer njihova eradikacija može smanjiti rezervoar virusa i na taj način smanjiti učestalost pojave CIN-a, karcinoma in situ i invazivnih karcinoma cerviksa u njihovih partnerica. Za ispravno postavljanje dijagnoze i odabir odgovarajuće terapijske tehnike predlažemo dijagnostičko-terapijski postupnik za HPV-genitalne infekcije u muškaraca.

Summary

Summary. Human papilloma virus infection is the most frequent sexually transmitted disease. HPV infections are connected with different diseases such as benign warts, condylomata acuminata, malignant cervical, vulvar, vaginal, penile and anal carcinoma. Peniscopy with HPV detection is a specific diagnostic method for diagnosis of subclinical HPV genital infection in asymptomatic men. Taking the samples for HPV detection from asymptomatic men with curette is more qualitative way of getting enough samples then taking swab with wooden stick or (tongue) depressor. Early diagnosis and treatment of HPV infections in men is of potential benefit because their eradication can reduce the viral reservoir and as the result of that the incidence of CIN, carcinoma in situ and invasive cervical carcinoma can be reduced. For the correct diagnosis and for choosing the adequate therapeutical technique, we suggest diagnostic-therapeutic guidelines for HPV genital infection in men.

Volumen: 9-10, 2009

Liječ Vjesn 2009;131:269–274

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