HAEMOSIDEROSIS BULBI IN A PATIENT WITH MYELODYSPLASTIC SYNDROME (MDS RAEB – 1)

Autori:

Andreja Lukenda, Zdenko Bujger, Ana Bajer-Feketić, Shkelqim Kica, Igor Petriček

Sažetak

Sažetak. Haemosiderosis bulbi je degenerativno stanje oka uzrokovano toksičkim efektima intracelularne akumulacije hemosiderina. Hemosiderin je produkt razgradnje hemoglobina. Najjača i najčešća toksička oštećenja događaju se u epitelnim stanicama očnih tkiva. Haemosiderosis bulbi je komplikacija dugotrajnog hemoftalmusa, krvarenja u staklastom tijelu, koje se nije spontano resorbiralo niti je operativno odstranjeno. Stanje je karakterizirano gubitkom osjeta svjetla i crvenom bojom intrabulbarnih tkiva. Uzrok hemoftalmusa kod našeg pacijenta je dugotrajna anemija zbog postojećeg mijelodisplastičkog sindroma (MDS RAEB-1).

Summary

Summary. Haemosiderosis bulbi is a degenerative condition of the eye bulb caused by the toxic effects of an intracellular accumulation of haemosiderin. Haemosiderin is a product of the decomposition of haemoglobin. The most common and severe damage takes place in the epithelial cells of the eye tissues. Haemosiderosis bulbi is a complication of the long existing haemophthalmus, the intravitreal bleeding, which is neither spontaneously resorbed nor operatively removed. The condition is characterized by the loss of light perception and the reddish colour of the intrabulbar tissues. The cause of the haemophthalmus in our patient is protracted anaemia due to pre-existing myelodysplastic syndrome (MDS RAEB – 1).