Ivica Grgurević, Tomislav Bokun, Renata Huzjan-Korunić, Mirjana Vukelić-Marković, Boris Brkljačić, Gordana Ivanac, Gorana Aralica, Tajana Štoos-Veić, Anita Lukić, Marko Banić, Milan Kujundžić
Aim: To demonstrate the results of contrast-enhanced ultrasound (CEUS) for diagnostic characterization of liver tumors (LT) in a tertiary-care hospital. Patients and methods: Results of CEUS examinations of LT in successively included patients from January 1st 2015 to December 31st 2016 were retrospectively analyzed. Definite diagnosis was made through standardized clinical workup including MRI and/or MSCT, tissue sam-pling (biopsy or cytology) in cases when imaging was inconclusive, as well as pathohistological analysis of resected specimens in patients that underwent surgery. Results: In 90 patients (48 M, 42 F; age 57±15) 132 LT were analyzed (68 benign and 64 malignant), with average size of 30 (8-130) mm. CEUS demonstrated excel-lent diagnostic performance to differentiate between benign and malignant LT (sensitivity 98.44%, specificity 83.82%, AUC 0.91), without adverse reactions. Conclusion: Our results demonstrate high diagnostic accuracy and safety of CEUS for characterization of LT.