CLINICAL GUIDELINES FOR DIAGNOSING, TREATMENT AND MONITORING PATIENTS WITH TESTICULAR CANCER – CROATIAN ONCOLOGY SOCIETY AND CROATIAN UROLOGY SOCIETY, CROATIAN MEDICAL ASSOCIATION
Autori:
Mislav Grgić, Ante Bolanča, Dubravka Ledina, Damir Gugić, Mladen Solarić, Tomislav Omrčen, Robert Zorica, Josip Galić, Davor Trnski, Josip Pasini, Ranka Štern Padovan, Marija Petković, Antonija Balenović, Antonio Juretić, Željko Kaštelan, Marija Gamulin
Sažetak
Tumori testisa najčešći su solidni tumori u muškaraca u dobi od 15. do 34. godine. Njihova je incidencija u svijetu podvostručena u posljednjih 40 godina. Tumori zametnih stanica obuhvaćaju 95% svih tumora testisa, a podijeljeni su u dva osnovna histološka tipa: seminomi i neseminomi. Osobito značenje daje im visok postotak izlječivosti i u diseminiranoj fazi bolesti. Ovom uspjehu najviše je pridonijela kemoterapija, ali i dalje je kirurgija neizostavni dio uspješnog liječenja. Kod znatnog dijela ovih bolesnika danas se nastoji odrediti terapijski minimum kojim se izbjegava niz nuspojava, a koji dovodi do jednakog uspjeha kao i donedavno agresivniji terapijski pristup. U tekstu koji slijedi iznesene su kliničke upute radi standardizacije dijagnostike, terapije i kontrole bolesnika s tumorima zametnih stanica testisa u Republici Hrvatskoj.
Summary
Testicular tumors are the most common solid tumors in men between 15 and 34 years of age. The worldwide incidence of these tumors has doubled in the past 40 years. Germ cell tumors comprise 95% of malignant tumors arising in the testes and they are classified either as seminoma or nonseminoma. Testicular cancers have a high cure rates even in disseminated stage of the disease. The chemotherapy mostly contributed to these results but surgery is an inevitable part of successful treatment. In a significant number of these patients treatment algorithms with minimum side effects are designed with the intention to maintain same cure rates as previously used, more aggressive therapy. The following text presents the clinical guidelines in order to standardize the procedures and criteria for diagnosis, management, treatment and follow-up of patients with testicular cancer in Republic of Croatia.
