NONSQUAMOUS CARCINOMAS OF THE LARYNX – 15 YEARS EXPERIENCE IN THE SINGLE INSTITUTION
Autori:
Mario Bilić, Drago Prgomet, Lana Kovač, Iva Topić, Vladimir Katić
Sažetak
Sažetak. Neepidermoidni tumori larinksa vrlo su rijetki. Pravodobna dijagnoza ovih tumora iznimno je važna zbog njihova različitog porijekla, izgleda, načina liječenja i prognoze. Polipoidne i submukozne lezije karakteristične su za ove tumore i vjerojatan razlog za relativno kasnu dijagnozu unatoč ranom postojanju simptoma. Prema porijeklu, neepidermoidni tumori larinksa mogu se podijeliti u one sekretornog porijekla, vezivnoga tkiva, limforetikularne, melanome i metastatske karcinome. U ovoj studiji tijekom 15 godina (1990–2005) u Klinici za bolesti uha, nosa i grla, kirurgiju glave i vrata, KBC-a Zagreb, liječen je 771 bolesnik s tumorom larinksa. Među njima bilo je 11 bolesnika s neepidermoidnim tumorom larinksa uključujući jedan slučaj neuroendokrinog tumora, leiomiosarkoma, fibrosarkoma, rabdomiosarkoma, adenoidnocističnog tumora, dva slučaja hondrosarkoma i tri slučaja mukoepidermoidnog karcinoma visokoga stupnja malignosti. Naše iskustvo u dijagnostici i liječenju ovih tumora predstavljeno je u ovom članku.
Summary
Summary. Nonsquamous carcinomas of the larynx are very rare and present a diverse group of diseases. Timely recognition of these tumors is extremely important for their different origin, appearance, and approach in the treatment and prognosis. Polypoid and submucosal lesions of the larynx are characteristic findings in these tumors, and probably the reason for late diagnosis even in the presence of symptoms. According to cell origin, nonsquamous carcinomas are classified into secretory, connective tissue, lymphoreticular, melanoma, or metastatic carcinoma. In this study, 771 laryngeal carcinomas treated during a 15-year (1990–2005) period at the Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center Zagreb, were reviewed to yield 11 cases of nonsquamous carcinoma, including one case of neuroendocrine carcinoma, leiomyosarcoma, fibrosarcoma, rhabdomyosarcoma, adenoid cystic carcinoma, and plasmacytoma, 2 cases of chondrosarcoma, and 3 cases of high-grade mucoepidermoid carcinoma. Our experience and treatment results for these tumors are presented.
