Effectivness and safety of exercise in idiopathic inflammatory myopathies – case report and review of the literature
Domagoj Andrić, Ružica Čunović-Dubroja, Darija Granec, Miroslav Mayer, Iva Milivojević, Lorena Petrač, Branimir Anić
Idiopathic inflammatory myopathies (IIM) are rare systemic autoimmune diseases characterized by proximal muscle weakness, evidence of muscle inflammation and damage and other extramuscular organ involvement, especially lungs.Early diagnosis and initiation of treatment reduces muscle inflammation and lowers the chance of developing extramuscular disease and muscle damage. Glucocorticoids are the cornerstone of pharmacological treatment, they are used in combination with immunosuppressive and immunomodulatory medications. Clinical and serological subtypes of IIM are very diverse, and they respond differently to pharmacological treatment. Therapeutic exercise in addition to medicaments is an important adjunct for the treatment of IIM. Improvement in muscle strength, impairment reduction, anti-inflammatory activity and increased metabolism in muscle fibers are all proven effects of exercise in many scientific studies.Exercise is a safe and effective treatment in both chronic and acute stage of myositis. Rehabilitation program should be individually adapted to every patient, and validated instruments should be used to measure clinically important change.In this paper we present a 3-year clinical course of a patient diagnozed with an anti-SRP positive myositis with a special review of stationary rehabilitation in the acute stage of the disease. Review of the literature is presented in discussion.
Branimir Anić, Darija Granec, Domagoj Andrić, Iva Milivojević, Lorena Petrač, Miroslav Mayer, Ružica Čunović-Dubroja